Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12597858 | 0.93 | P2RX7 (0.34) | HTR6HTR2CPARP1P2RX7 | |
| SCHEMBL1987426 | 0.79 | HTR7 (0.33) | HTR6PARP1P2RX7 | |
| SCHEMBL14659109 | 0.78 | P2RX7 (0.36) | HTR6HTR2CPARP1HTR2AP2RX7 | |
| SCHEMBL1988565 | 0.75 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL1986144 | 0.74 | P2RX7 (0.42) | HTR6HTR2CP2RX7 | |
| SCHEMBL1990730 | 0.72 | HTR2C (0.44) | HTR6HTR2CPARP1HTR2AP2RX7 | |
| SCHEMBL1981671 | 0.70 | HTR2C (0.39) | HTR2CPARP1HTR2AP2RX7 | |
| SCHEMBL14671502 | 0.69 | KDM1A (0.45) | P2RX7 | |
| SCHEMBL12597614 | 0.69 | P2RX7 (0.38) | HTR6HTR2CPARP1HTR2AP2RX7 | |
| SCHEMBL31694729 | 0.68 | TUBB4A (0.41) | HTR6HTR2CPARP1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509977-B1 | NOVEL CATIONIC 4-AMINOINDOLES, DYE COMPOSITION COMPRISING A CATIONIC 4-AMINOINDOLE, PROCESSES THEREFOR AND USES THEREOF | OREAL (FR) | 2014-03-26 | — | — | EP | claimed |
| US-8568491-B2 | Cationic 4-aminoindoles, dye composition comprising a cationic 4-aminoindole, processes therefor and uses thereof | L'OREAL (FR) | 2013-10-29 | — | — | US | claimed |
| US-20130025618-A1 | NOVEL CATIONIC 4-AMINOINDOLES, DYE COMPOSITION COMPRISING A CATIONIC 4-AMINOINDOLE, PROCESSES THEREFOR AND USES THEREOF | L'OREAL (FR) | 2013-01-31 | — | — | US | claimed |
| WO-2011069952-A1 | NOVEL CATIONIC 4-AMINOINDOLES, DYE COMPOSITION COMPRISING A CATIONIC 4-AMINOINDOLE, PROCESSES THEREFOR AND USES THEREOF | L'OREAL (FR) | 2011-06-16 | — | — | WO | claimed |
| EP-2509977-B1 | NOVEL CATIONIC 4-AMINOINDOLES, DYE COMPOSITION COMPRISING A CATIONIC 4-AMINOINDOLE, PROCESSES THEREFOR AND USES THEREOF | OREAL (FR) | 2014-03-26 | — | — | EP | disclosed |
| EP-2509977-B1 | NOVEL CATIONIC 4-AMINOINDOLES, DYE COMPOSITION COMPRISING A CATIONIC 4-AMINOINDOLE, PROCESSES THEREFOR AND USES THEREOF | OREAL (FR) | 2014-03-26 | — | — | EP | disclosed |
| US-8568491-B2 | Cationic 4-aminoindoles, dye composition comprising a cationic 4-aminoindole, processes therefor and uses thereof | L'OREAL (FR) | 2013-10-29 | — | — | US | disclosed |
| US-20130025618-A1 | NOVEL CATIONIC 4-AMINOINDOLES, DYE COMPOSITION COMPRISING A CATIONIC 4-AMINOINDOLE, PROCESSES THEREFOR AND USES THEREOF | L'OREAL (FR) | 2013-01-31 | — | — | US | disclosed |
| WO-2011069952-A1 | NOVEL CATIONIC 4-AMINOINDOLES, DYE COMPOSITION COMPRISING A CATIONIC 4-AMINOINDOLE, PROCESSES THEREFOR AND USES THEREOF | L'OREAL (FR) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130025618-A1 | NOVEL CATIONIC 4-AMINOINDOLES, DYE COMPOSITION COMPRISING A CATIONIC 4-AMINOINDOLE, PROCESSES THEREFOR AND USES THEREOF | TPH1, TPH2, FARS2 | HTR6 199/4885HTR2C 49/4885PARP1 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.