SCHEMBL19909035

SCHEMBL19909035

N#Cc1cc(-n2c3ccccc3c3ccc(C#N)cc32)c(-c2ccncc2)c(-n2c3ccccc3c3ccc(C#N)cc32)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 3/20 0.38
MAPK14 Q16539 4/20 0.37
ABCG2 Q9UNQ0 1/20 0.36
CSNK1A1 P48729 2/20 0.36
CSNK1D P48730 2/20 0.36
CYP19A1 P11511 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
SLC6A2 P23975 1/20 0.35
PKN1 Q16512 1/20 0.35
PKN2 Q16513 1/20 0.35
USP2 O75604 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
CASP1 P29466 1/20 0.34
KDR P35968 2/20 0.33
ENPP3 O14638 1/20 0.33
CDC7 O00311 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909036 0.94 FLT3 (0.39) FLT3MAPK14CSNK1A1CSNK1DCYP19A1
SCHEMBL21757798 0.94 MAPK14 (0.40) FLT3MAPK14ABCG2CSNK1A1CSNK1D
SCHEMBL19909037 0.93 MAPK14 (0.38) FLT3MAPK14ABCG2CSNK1A1CSNK1D
SCHEMBL19909478 0.92 FLT3 (0.41) FLT3MAPK14CSNK1A1CSNK1DCYP11B2
SCHEMBL19913143 0.90 MAPK14 (0.35) FLT3MAPK14ABCG2CSNK1A1CSNK1D
SCHEMBL19913141 0.90 MAPK14 (0.35) FLT3MAPK14ABCG2CSNK1A1CSNK1D
SCHEMBL25658929 0.90 PTGER4 (0.36) ENPP3PTGER4
SCHEMBL19909164 0.90 USP2 (0.40) FLT3MAPK14ABCG2USP2CYP1A2
SCHEMBL19913140 0.89 MAPK14 (0.37) FLT3MAPK14ABCG2CYP19A1CYP11B2
SCHEMBL19909117 0.89 MAPK14 (0.39) FLT3MAPK14ABCG2CSNK1A1CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 FLT3 2571/4885MAPK14 2544/4885ABCG2 624/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 FLT3 3269/4885MAPK14 2787/4885ABCG2 3492/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 FLT3 2571/4885MAPK14 2544/4885ABCG2 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.