SCHEMBL19913141

SCHEMBL19913141

N#Cc1cc(-n2c3ccccc3c3ccc(-n4c5ccccc5c5ccccc54)cc32)c(-c2ccncc2)c(-n2c3ccccc3c3ccc(-n4c5ccccc5c5ccccc54)cc32)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 4/20 0.35
SLC6A2 P23975 1/20 0.34
BRAF P15056 1/20 0.34
KDR P35968 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FLT3 P36888 2/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
CSNK1A1 P48729 1/20 0.32
CSNK1D P48730 1/20 0.32
PTGER4 P35408 1/20 0.32
MET P08581 1/20 0.31
MAPK10 P53779 2/20 0.31
MAPK9 P45984 1/20 0.31
USP2 O75604 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913143 1.00 MAPK14 (0.35) MAPK14SLC6A2BRAFKDRKDM4E
SCHEMBL19913155 0.93 MAPK14 (0.35) MAPK14SLC6A2BRAFKDRKDM4E
SCHEMBL19913148 0.93 MAPK14 (0.35) MAPK14SLC6A2BRAFKDRKDM4E
SCHEMBL21757798 0.91 MAPK14 (0.40) MAPK14SLC6A2FLT3ABCG2CYP19A1
SCHEMBL19909035 0.90 FLT3 (0.38) MAPK14SLC6A2BRAFKDRFLT3
SCHEMBL21414187 0.88 KDM4E (0.37) KDM4EATML3MBTL1PTGER4HPGD
SCHEMBL19913150 0.87 MAPK14 (0.39) MAPK14FLT3ABCG2METUSP2
SCHEMBL19913140 0.87 MAPK14 (0.37) MAPK14SLC6A2KDM4EFLT3ABCG2
SCHEMBL19909117 0.87 MAPK14 (0.39) MAPK14SLC6A2BRAFKDRFLT3
SCHEMBL19909478 0.87 FLT3 (0.41) MAPK14SLC6A2BRAFKDRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MAPK14 2544/4885SLC6A2 1996/4885BRAF 1572/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 MAPK14 2787/4885SLC6A2 3475/4885BRAF 1780/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MAPK14 2544/4885SLC6A2 1996/4885BRAF 1572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.