SCHEMBL19909059

SCHEMBL19909059

Cc1ccc(-c2ccc3c4ccc(-c5ccc(C)cc5)cc4n(-c4cc(-c5ccncc5)cc(-n5c6cc(-c7ccc(C)cc7)ccc6c6ccc(-c7ccc(C)cc7)cc65)c4C#N)c3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 2/20 0.37
PIK3CD O00329 1/20 0.37
PIK3CB P42338 1/20 0.37
MTOR P42345 1/20 0.37
PIK3CG P48736 1/20 0.37
CHEK1 O14757 1/20 0.37
AURKA O14965 1/20 0.35
KDR P35968 1/20 0.35
AURKB Q96GD4 1/20 0.35
METAP2 P50579 3/20 0.35
PDE10A Q9Y233 1/20 0.35
NTRK1 P04629 1/20 0.34
PIM1 P11309 1/20 0.34
ACVR1 Q04771 1/20 0.34
FLT3 P36888 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALDH1A1 P00352 1/20 0.34
DYRK3 O43781 1/20 0.33
ROCK2 O75116 1/20 0.33
RPS6KA5 O75582 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913187 0.94 PDE9A (0.39) PIK3CAPIK3CDPIK3CBMTORPIK3CG
SCHEMBL19909060 0.94 KDM5B (0.39) PIK3CACHEK1METAP2PDE10AFLT3
SCHEMBL19913182 0.93 PIP4K2A (0.41) PIK3CAPIK3CDPIK3CBMTORPIK3CG
SCHEMBL19909153 0.92 TDP1 (0.35) PIK3CAPIK3CDPIK3CBMTORPIK3CG
SCHEMBL19909426 0.90 PIP4K2A (0.42) CHEK1ALDH1A1MAP4K4CDK1CDK2
SCHEMBL19909062 0.90 PIK3CD (0.39) PIK3CAPIK3CDPIK3CBMTORPIK3CG
SCHEMBL19909057 0.88 ABL1 (0.39) PIK3CACHEK1FLT3TDP1ALDH1A1
SCHEMBL19913188 0.88 MAPK14 (0.38) CHEK1PDE10AFLT3ALDH1A1
SCHEMBL19909112 0.88 ADORA1 (0.42) PIK3CAPRKACACLK2GSK3AGSK3B
SCHEMBL19908908 0.88 FLT3 (0.40) CHEK1KDRMETAP2PDE10AFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 PIK3CA 3731/4885PIK3CD 4090/4885PIK3CB 3848/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 PIK3CA 3731/4885PIK3CD 4090/4885PIK3CB 3848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.