SCHEMBL19909162

SCHEMBL19909162

Cc1nc(C)nc(-c2ccc3c(c2)c2cc(-c4nc(C)nc(C)n4)ccc2n3-c2cc(-c3ccncc3)c(-n3c4ccc(-c5nc(C)nc(C)n5)cc4c4cc(-c5nc(C)nc(C)n5)ccc43)cc2C#N)n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 4/20 0.37
PDE3A Q14432 4/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 1/20 0.37
PDE5A O76074 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
PTGS1 P23219 1/20 0.37
PDE4A P27815 1/20 0.37
CYP2C19 P33261 1/20 0.37
BLM P54132 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
XDH P47989 1/20 0.35
SQOR Q9Y6N5 2/20 0.34
AAK1 Q2M2I8 3/20 0.33
CHEK1 O14757 1/20 0.33
GSK3B P49841 1/20 0.33
MKNK1 Q9BUB5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909160 0.96 SQOR (0.35) PDE3BPDE3ALMNAKDM4EPDE5A
SCHEMBL19909490 0.92 PDE3B (0.38) PDE3BPDE3ALMNAKDM4EPDE5A
SCHEMBL19913133 0.91 PDE3B (0.37) PDE3BPDE3ALMNAKDM4EPDE5A
SCHEMBL19909480 0.89 SQOR (0.35) PDE3BPDE3ALMNAKDM4EPDE5A
SCHEMBL19909163 0.89 SQOR (0.35) PDE3BPDE3ALMNAKDM4EPDE5A
SCHEMBL22170449 0.88
SCHEMBL20619455 0.87 XDH (0.39) KDM4EHPGDTSHRXDHSQOR
SCHEMBL19909301 0.87 SQOR (0.40) LMNAHPGDTSHRCYP2C19SQOR
SCHEMBL19909011 0.86 PIK3CD (0.39) PDE3BPDE3ALMNAKDM4EPDE5A
SCHEMBL19909012 0.85 PDE3B (0.38) PDE3BPDE3ALMNAKDM4EPDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 PDE3B 1366/4885PDE3A 1793/4885LMNA 3815/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 PDE3B 4094/4885PDE3A 4387/4885LMNA 4076/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 PDE3B 1366/4885PDE3A 1793/4885LMNA 3815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.