Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828345 | 0.83 | RXRA (0.53) | KDM4EATMTAS2R14RAB9AEPHX2 | |
| SCHEMBL19910455 | 0.81 | L3MBTL1 (0.50) | KDM4EALDH1A1LTA4HMEN1KMT2A | |
| SCHEMBL19910376 | 0.79 | ALDH1A1 (0.48) | KDM4EALDH1A1LTA4HMEN1KMT2A | |
| SCHEMBL19910374 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1LTA4HMEN1KMT2A | |
| SCHEMBL19910479 | 0.76 | LPAR1 (0.55) | KDM4EALDH1A1LTA4HMEN1KMT2A | |
| SCHEMBL19910426 | 0.76 | GAA (0.59) | KDM4EALDH1A1LTA4HMEN1KMT2A | |
| SCHEMBL4124943 | 0.76 | EPHX2 (0.55) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL19868556 | 0.75 | TAS2R14 (0.40) | KDM4EALDH1A1LTA4HMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29137808 | 0.73 | ALDH1A1 (0.59) | KDM4EALDH1A1MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL29690748 | 0.73 | ALDH1A1 (0.59) | KDM4EALDH1A1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065738-B1 | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |