Sugi Predict

Sugi Predict / Compounds / SCHEMBL19913147

SCHEMBL19913147

SCHEMBL19913147

Cc1ccccc1-c1ccc2c(c1)c1ccccc1n2-c1cc(C#N)cc(-n2c3ccccc3c3cc(-c4ccccc4C)ccc32)c1-c1ccncc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 5/20 0.37
▸ CYP11B1 P15538 2/20 0.37
▸ CYP11B2 P19099 2/20 0.37
▸ PTGER4 P35408 1/20 0.35
▸ AR P10275 1/20 0.35
▸ ALDH1A1 P00352 3/20 0.34
▸ CYP1A2 P05177 3/20 0.34
▸ CYP3A4 P08684 3/20 0.34
▸ CYP2C19 P33261 3/20 0.34
▸ CLK4 Q9HAZ1 3/20 0.34
▸ CYP2D6 P10635 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ TP53 P04637 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ GRIA2 P42262 1/20 0.33
▸ GRIA4 P48058 1/20 0.33
▸ CSNK1A1 P48729 1/20 0.33
▸ CSNK1D P48730 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913156 0.97 CYP11B1 (0.39) MAPK14CYP11B1CYP11B2ARALDH1A1
SCHEMBL19909333 0.94 MAPK14 (0.37) MAPK14CYP11B1CYP11B2ARALDH1A1
SCHEMBL25658932 0.91 PTGER4 (0.39) CYP11B1CYP11B2PTGER4ARALDH1A1
SCHEMBL19909070 0.91 CYP11B1 (0.35) MAPK14CYP11B1CYP11B2PTGER4ALDH1A1
SCHEMBL19908896 0.90 CYP11B1 (0.39) MAPK14CYP11B1CYP11B2ARALDH1A1
SCHEMBL19913332 0.89 SQOR (0.37) MAPK14CYP11B1CYP11B2PTGER4ALDH1A1
SCHEMBL21414116 0.89 AR (0.38) PTGER4ARALDH1A1CYP1A2CYP3A4
SCHEMBL19908924 0.88 CYP1A2 (0.37) MAPK14ALDH1A1CYP1A2CYP3A4CYP2C19
SCHEMBL19908958 0.88 MAPK14 (0.37) MAPK14CYP11B1CYP11B2PTGER4ALDH1A1
SCHEMBL19913153 0.87 MAPK14 (0.40) MAPK14PTGER4ALDH1A1LMNACSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 — — US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 — — US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MAPK14 2544/4885CYP11B1 610/4885CYP11B2 402/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 MAPK14 2787/4885CYP11B1 1400/4885CYP11B2 965/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MAPK14 2544/4885CYP11B1 610/4885CYP11B2 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.