Sugi Predict

Sugi Predict / Compounds / SCHEMBL19913153

SCHEMBL19913153

SCHEMBL19913153

Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)cc(-n3c4ccccc4c4cc(-c5ccc(C)cc5)ccc43)c2-c2ccncc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 5/20 0.40
▸ PDE9A O76083 2/20 0.38
▸ PDE1C Q14123 2/20 0.38
▸ FLT3 P36888 2/20 0.37
▸ PTGER4 P35408 2/20 0.36
▸ MAPKAPK2 P49137 1/20 0.36
▸ PIK3CD O00329 1/20 0.35
▸ PIK3CA P42336 1/20 0.35
▸ PIK3CB P42338 1/20 0.35
▸ MTOR P42345 1/20 0.35
▸ PIK3CG P48736 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ CSNK1A1 P48729 1/20 0.34
▸ CSNK1D P48730 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909067 0.94 MAPKAPK2 (0.39) MAPK14FLT3MAPKAPK2PIK3CDPIK3CA
SCHEMBL19908939 0.94 MAPK14 (0.40) MAPK14PDE9APDE1CFLT3MAPKAPK2
SCHEMBL19908941 0.93 MAPK14 (0.41) MAPK14PDE9APDE1CFLT3PTGER4
SCHEMBL19913139 0.92 MAPK14 (0.37) MAPK14PDE9APDE1CFLT3PTGER4
SCHEMBL19909350 0.92 MAPK14 (0.39) MAPK14FLT3PIK3CACSNK1A1CSNK1D
SCHEMBL19908925 0.92 MAPK14 (0.39) MAPK14FLT3PTGER4CSNK1A1CSNK1D
SCHEMBL19913154 0.92 MAPK14 (0.42) MAPK14FLT3PTGER4ALDH1A1CSNK1A1
SCHEMBL19908958 0.90 MAPK14 (0.37) MAPK14PDE9APDE1CFLT3PTGER4
SCHEMBL19909114 0.90 MAPK14 (0.39) MAPK14FLT3PTGER4CSNK1A1CSNK1D
SCHEMBL21414129 0.90 PDE9A (0.39) PDE9APDE1CPTGER4MAPKAPK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 — — US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 — — US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MAPK14 2544/4885PDE9A 2525/4885PDE1C 4780/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 MAPK14 2787/4885PDE9A 4739/4885PDE1C 4778/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MAPK14 2544/4885PDE9A 2525/4885PDE1C 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.