SCHEMBL19909114

SCHEMBL19909114

N#Cc1cc(C#N)cc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)cc(-n3c4ccccc4c4cc(-c5cc(C#N)cc(C#N)c5)ccc43)c2-c2ccncc2)c1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 5/20 0.39
CSNK1A1 P48729 1/20 0.36
CSNK1D P48730 1/20 0.36
FLT3 P36888 2/20 0.34
PTGER4 P35408 2/20 0.34
SLC6A2 P23975 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.32
USP2 O75604 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
CASP1 P29466 1/20 0.32
PGR P06401 1/20 0.32
GRM5 P41594 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19908989 0.94 MAPK14 (0.39) MAPK14CSNK1A1CSNK1DFLT3GRM5
SCHEMBL19909475 0.93 CYP1A2 (0.40) MAPK14FLT3ABCG2USP2CYP1A2
SCHEMBL19909350 0.93 MAPK14 (0.39) MAPK14CSNK1A1CSNK1DFLT3ABCG2
SCHEMBL19908925 0.93 MAPK14 (0.39) MAPK14CSNK1A1CSNK1DFLT3PTGER4
SCHEMBL19909117 0.93 MAPK14 (0.39) MAPK14CSNK1A1CSNK1DFLT3PTGER4
SCHEMBL19908941 0.91 MAPK14 (0.41) MAPK14CSNK1A1CSNK1DFLT3PTGER4
SCHEMBL21414143 0.90 PGR (0.35) PTGER4HPGDCASP1PGR
SCHEMBL21757798 0.90 MAPK14 (0.40) MAPK14CSNK1A1CSNK1DFLT3PTGER4
SCHEMBL19913153 0.90 MAPK14 (0.40) MAPK14CSNK1A1CSNK1DFLT3PTGER4
SCHEMBL19909037 0.89 MAPK14 (0.38) MAPK14CSNK1A1CSNK1DFLT3PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MAPK14 2544/4885CSNK1A1 4231/4885CSNK1D 3662/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 MAPK14 2787/4885CSNK1A1 2962/4885CSNK1D 1514/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MAPK14 2544/4885CSNK1A1 4231/4885CSNK1D 3662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.