Sugi Predict

Sugi Predict / Compounds / SCHEMBL19913154

SCHEMBL19913154

SCHEMBL19913154

Cc1cccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)cc(-n3c4ccccc4c4cc(-c5cccc(C)c5)ccc43)c2-c2ccncc2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 6/20 0.42
▸ PTGER4 P35408 1/20 0.37
▸ CYP11B1 P15538 1/20 0.35
▸ CYP11B2 P19099 1/20 0.35
▸ GRIA2 P42262 1/20 0.35
▸ GRIA4 P48058 1/20 0.35
▸ FLT3 P36888 2/20 0.34
▸ SIRT2 Q8IXJ6 2/20 0.34
▸ F2 P00734 1/20 0.34
▸ PLAU P00749 1/20 0.34
▸ ELANE P08246 1/20 0.34
▸ CTRB1 P17538 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913159 0.96 MAPK14 (0.45) MAPK14CYP11B1CYP11B2GRIA2GRIA4
SCHEMBL19913160 0.94 MAPK14 (0.42) MAPK14CYP11B1CYP11B2GRIA2GRIA4
SCHEMBL19908941 0.93 MAPK14 (0.41) MAPK14PTGER4FLT3GRM5CSNK1A1
SCHEMBL19913153 0.92 MAPK14 (0.40) MAPK14PTGER4FLT3KDM4EALDH1A1
SCHEMBL19909475 0.90 CYP1A2 (0.40) MAPK14FLT3ALDH1A1CYP1A2CYP2C9
SCHEMBL19913139 0.90 MAPK14 (0.37) MAPK14PTGER4CYP11B2FLT3F2
SCHEMBL19909350 0.90 MAPK14 (0.39) MAPK14FLT3CYP1A2CYP2C9HPGD
SCHEMBL21414127 0.89 PTGER4 (0.37) PTGER4CYP11B1CYP11B2GRIA2GRIA4
SCHEMBL21546728 0.89 ALDH1A1 (0.39) PTGER4GRIA2GRIA4SIRT2ELANE
SCHEMBL19913158 0.89 MAPK14 (0.45) MAPK14CYP11B1CYP11B2GRIA2GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 — — US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 — — US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MAPK14 2544/4885PTGER4 1123/4885CYP11B1 610/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 MAPK14 2787/4885PTGER4 1386/4885CYP11B1 1400/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MAPK14 2544/4885PTGER4 1123/4885CYP11B1 610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.