SCHEMBL19917249

SCHEMBL19917249

C=C/C=C\C=C(/C=C)Oc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 2/20 0.37
CYP19A1 P11511 1/20 0.34
THRB P10828 1/20 0.34
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
AKT1 P31749 1/20 0.31
SRC P12931 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
RAD51 Q06609 1/20 0.30
LTA4H P09960 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18456259 0.86 TGM2 (0.40) TGM2CYP19A1THRBATMTDP1
SCHEMBL14449399 0.84 TGM2 (0.36) TGM2CYP19A1THRBATMTDP1
SCHEMBL25141032 0.79 TGM2 (0.38) TGM2CYP19A1THRBATMTDP1
SCHEMBL19558477 0.78 THRB (0.34) TGM2THRBATMTDP1L3MBTL1
SCHEMBL24554358 0.78 ELANE (0.34) CYP19A1THRBATMTDP1L3MBTL1
SCHEMBL19266440 0.77 THRB (0.33) TGM2THRB
SCHEMBL22504926 0.76 TGM2 (0.36) TGM2THRBATMTDP1L3MBTL1
SCHEMBL19917284 0.76 TGM2 (0.36) TGM2THRBATMTDP1L3MBTL1
SCHEMBL19322527 0.76 TGM2 (0.41) TGM2CYP19A1THRBATMTDP1
SCHEMBL20102792 0.75 TGM2 (0.35) TGM2THRBATMTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639338-B1 Compound producing method, and compound KUREHA CORPORATION (JP) 2023-05-02 US disclosed
US-20180057429-A1 SYSTEM AND METHOD FOR PREPARING AROMATIC DERIVATIVE LCY Chemical Corp. (TW) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057429-A1 SYSTEM AND METHOD FOR PREPARING AROMATIC DERIVATIVE AHR, BLVRB, RARB TGM2 3890/4885CYP19A1 389/4885THRB 450/4885
US-11639338-B1 Compound producing method, and compound CA7, CYP3A7, GANC TGM2 793/4885CYP19A1 495/4885THRB 4538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.