Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 11/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917773 | 0.93 | TRPA1 (0.45) | TRPA1PTGESMEN1KMT2AWNT3A | |
| SCHEMBL19917752 | 0.89 | TRPA1 (0.41) | TRPA1CCR1PTGESTDP1TP53 | |
| SCHEMBL19917730 | 0.88 | TRPA1 (0.44) | TRPA1TP53 | |
| SCHEMBL19917733 | 0.88 | TRPA1 (0.55) | TRPA1MEN1KMT2A | |
| SCHEMBL19917781 | 0.87 | TRPA1 (0.41) | TRPA1CCR1PTGESTDP1TP53 | |
| SCHEMBL19917662 | 0.86 | TRPA1 (0.43) | TRPA1MEN1KMT2ATP53 | |
| SCHEMBL19917696 | 0.85 | TRPA1 (0.48) | TRPA1 | |
| SCHEMBL16894136 | 0.83 | TRPA1 (0.60) | TRPA1 | |
| SCHEMBL19917744 | 0.83 | TRPA1 (0.45) | TRPA1CCR1PTGESTDP1MEN1 | |
| SCHEMBL16894139 | 0.81 | TRPA1 (0.47) | TRPA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900642-B1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-02-28 | — | — | EP | disclosed |