SCHEMBL19918567

SCHEMBL19918567

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc(-n5c6ccc(-c7ccc8oc9cc%10c%11c(cccc%11c9c8c7)-c7ccccc7-%10)cc6c6ccc(-c7cccc(-c8cccc(-c9nc(-c%10cccc(-c%11ccccc%11)c%10)nc(-c%10cccc(-n%11c%12ccccc%12c%12cc(-c%13ccc%14oc%15cc%16c%17c(cccc%17c%15c%14c%13)-c%13ccccc%13-%16)ccc%12%11)c%10)n9)c8)c7)cc65)c4)n3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPSE Q9Y251 2/20 0.32
PDE10A Q9Y233 1/20 0.31
PLA2G10 O15496 1/20 0.30
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30
TSPO P30536 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918569 0.95 L3MBTL1 (0.33) HPSEPDE10APLA2G10PLA2G2APLA2G4A
SCHEMBL19918435 0.92 ATM (0.35) HPSEPDE10APLA2G10PLA2G2APLA2G4A
SCHEMBL19918540 0.91 RAC2 (0.31) PLA2G10PLA2G2APLA2G4ATSPO
SCHEMBL19918566 0.91 L3MBTL1 (0.33) PLA2G10PLA2G2APLA2G4ATSPO
SCHEMBL19918434 0.91 ATM (0.36) PDE10APLA2G10PLA2G2APLA2G4ATSPO
SCHEMBL19918436 0.91 ATM (0.36) PDE10APLA2G10PLA2G2APLA2G4ATSPO
SCHEMBL19918684 0.90 MEN1 (0.33)
SCHEMBL19918534 0.89 TSPO (0.33) PLA2G10PLA2G2APLA2G4ATSPO
SCHEMBL19918686 0.88
SCHEMBL19918573 0.88 PLA2G2A (0.32) PLA2G10PLA2G2APLA2G4ATSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038400-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed