SCHEMBL19918573

SCHEMBL19918573

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4cc(-c5ccc6oc7cc8c9c(cccc9c7c6c5)-c5ccccc5-8)ccc43)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.32
PLA2G4A P47712 3/20 0.32
PLA2G10 O15496 1/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
TSHR P16473 2/20 0.32
MAPK1 P28482 2/20 0.32
HSD17B10 Q99714 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CASP1 P29466 1/20 0.32
HIF1A Q16665 1/20 0.32
TSPO P30536 1/20 0.31
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918534 0.99 TSPO (0.33) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL19918685 0.97 CHEK2 (0.33) PLA2G2APLA2G4APLA2G10TSPO
SCHEMBL24030881 0.97 ALDH1A1 (0.33) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL19918687 0.95 PLA2G2A (0.31) PLA2G2APLA2G4APLA2G10
SCHEMBL19918566 0.93 L3MBTL1 (0.33) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL19918569 0.92 L3MBTL1 (0.33) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL19918574 0.92 TUBB4A (0.33) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL19039200 0.92 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL19918540 0.91 RAC2 (0.31) PLA2G2APLA2G4APLA2G10TSPO
SCHEMBL19918575 0.91 ALDH1A1 (0.33) ALDH1A1HPGDTSHRMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038400-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed