Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817025 | 0.80 | HSD17B10 (0.39) | POLBTSHRKDM4EALDH1A1 | |
| SCHEMBL11551897 | 0.70 | HTT (0.48) | DNM1RAD52LMNATSHR | |
| SCHEMBL4532619 | 0.70 | ALDH1A1 (0.41) | POLBTSHRKDM4EALDH1A1 | |
| SCHEMBL12260233 | 0.67 | RXFP1 (0.67) | LMNATP53 | |
| SCHEMBL21935727 | 0.66 | PORCN (0.58) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL21936455 | 0.66 | PORCN (0.51) | CYP2D6 | |
| SCHEMBL10587862 | 0.66 | ALDH1A1 (0.38) | POLBKDM4EALDH1A1 | |
| SCHEMBL12260312 | 0.65 | RXFP1 (0.66) | LMNAALOX15TP53 | |
| SCHEMBL11026757 | 0.63 | ALDH1A1 (0.60) | DNM1POLBALOX15TSHRKDM4E | |
| SCHEMBL8773743 | 0.63 | DNM1 (0.76) | DNM1CYP2C9CYP2C19POLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018039641-A1 | METHODS AND COMPOUNDS FOR TREATING ALCOHOL USE DISORDERS AND ASSOCIATED DISEASES | PHARMATROPHIX, INC. (US) | 2018-03-01 | — | — | WO | disclosed |