Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PORCN | Q9H237 | 10/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.39 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21935727 | 0.93 | PORCN (0.58) | PORCNCYP3A4CYP2D6CYP1A2KCNH2 | |
| SCHEMBL20079782 | 0.76 | MAPK14 (0.40) | PORCNCYP3A4CYP1A2WNT3AMAPT | |
| SCHEMBL17626334 | 0.75 | PORCN (0.85) | PORCNCYP1A2MAPT | |
| SCHEMBL20161623 | 0.74 | ALDH1A1 (0.46) | MAPT | |
| SCHEMBL16835775 | 0.70 | PORCN (0.84) | PORCNCYP3A4CYP2D6CYP1A2KCNH2 | |
| SCHEMBL21133501 | 0.70 | TP53 (0.55) | MAPT | |
| SCHEMBL21935472 | 0.69 | DCTPP1 (0.46) | MAPT | |
| SCHEMBL21935831 | 0.69 | DEGS1 (0.47) | WNT3AMAPT | |
| SCHEMBL20079704 | 0.68 | TRPA1 (0.37) | CYP3A4CYP1A2MAPT | |
| Etc-159 SCHEMBL17626176 | 0.67 | PORCN (1.00) | PORCNCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999699-B1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY SCIENCE TECH & RES (SG) | 2020-04-29 | — | — | EP | disclosed |