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SCHEMBL1992300

SCHEMBL1992300

CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1COCC(F)(F)F

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.42
▸ LMNA P02545 2/20 0.34
▸ PDK1 Q15118 1/20 0.33
▸ PDK2 Q15119 1/20 0.33
▸ PDK3 Q15120 1/20 0.33
▸ PDK4 Q16654 1/20 0.33
▸ MRGPRX4 Q96LA9 2/20 0.33
▸ TSHR P16473 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HPGD P15428 3/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ HSD17B10 Q99714 2/20 0.32
▸ ACLY P53396 2/20 0.32
▸ CYP2C19 P33261 2/20 0.32
▸ USP2 O75604 1/20 0.32
▸ CYP1A2 P05177 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31223249 0.90 ALDH1A1 (0.36) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL16547015 0.90 ALDH1A1 (0.36) ALDH1A1LMNATSHRSMN1; SMN2MEN1
SCHEMBL28573030 0.88 PDK2 (0.38) ALDH1A1LMNAPDK1PDK2PDK3
SCHEMBL28759767 0.84 ALDH1A1 (0.36) ALDH1A1LMNATSHRSMN1; SMN2MEN1
SCHEMBL1702374 0.82 CYP1A2 (0.36) ALDH1A1LMNACYP2C19CYP1A2MAPT
SCHEMBL31299930 0.82 CYP1A2 (0.36) ALDH1A1LMNACYP2C19CYP1A2MAPT
SCHEMBL16021132 0.82 ALDH1A1 (0.33) ALDH1A1LMNATSHRSMN1; SMN2EPAS1
SCHEMBL9078012 0.81 LMNA (0.39) ALDH1A1LMNATSHRHPGDACLY
Tembotrione SCHEMBL116424 0.81 HPD (0.38) ALDH1A1CYP2C19CYP1A2CYP2C9MEN1
Tembotrione SCHEMBL3225813 0.81 HPD (0.38) ALDH1A1CYP2C19CYP1A2CYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692052-A1 PREPARATION METHOD FOR 1-[2-CHLORO-3-(BROMOMETHYL)-4-(METHYLSULFONYL)PHENYL]ETHANONE AND THE USE OF SAME Nutrichem Company Limited (CN) 2026-02-11 — — EP claimed
WO-2024239843-A1 PREPARATION METHOD FOR 1-[2-CHLORO-3-(BROMOMETHYL)-4-(METHYLSULFONYL)PHENYL]ETHANONE AND THE USE OF SAME 北京颖泰嘉和生物科技股份有限公司 2024-11-28 — — WO claimed
CN-119019300-A Preparation and application of cyclosulfamide intermediate 北京颖泰嘉和生物科技股份有限公司 2024-11-26 — — CN claimed
CN-119019299-A Preparation method and application of 1- [ 2-chloro-3- (bromomethyl) -4- (methylsulfonyl) phenyl ] ethanone 北京颖泰嘉和生物科技股份有限公司 2024-11-26 — — CN claimed
EP-4692052-A1 PREPARATION METHOD FOR 1-[2-CHLORO-3-(BROMOMETHYL)-4-(METHYLSULFONYL)PHENYL]ETHANONE AND THE USE OF SAME Nutrichem Company Limited (CN) 2026-02-11 — — EP disclosed
EP-4692052-A1 PREPARATION METHOD FOR 1-[2-CHLORO-3-(BROMOMETHYL)-4-(METHYLSULFONYL)PHENYL]ETHANONE AND THE USE OF SAME Nutrichem Company Limited (CN) 2026-02-11 — — EP disclosed
EP-4686757-A1 INHIBITORS OF EXPRESSION AND/OR FUNCTION e-therapeutics PLC (GB) 2026-02-04 — — EP disclosed
WO-2024239843-A1 PREPARATION METHOD FOR 1-[2-CHLORO-3-(BROMOMETHYL)-4-(METHYLSULFONYL)PHENYL]ETHANONE AND THE USE OF SAME 北京颖泰嘉和生物科技股份有限公司 2024-11-28 — — WO disclosed
WO-2024239843-A1 PREPARATION METHOD FOR 1-[2-CHLORO-3-(BROMOMETHYL)-4-(METHYLSULFONYL)PHENYL]ETHANONE AND THE USE OF SAME 北京颖泰嘉和生物科技股份有限公司 2024-11-28 — — WO disclosed
CN-119019300-A Preparation and application of cyclosulfamide intermediate 北京颖泰嘉和生物科技股份有限公司 2024-11-26 — — CN disclosed
CN-119019299-A Preparation method and application of 1- [ 2-chloro-3- (bromomethyl) -4- (methylsulfonyl) phenyl ] ethanone 北京颖泰嘉和生物科技股份有限公司 2024-11-26 — — CN disclosed
CN-114560795-B Method for preparing cyclosulfamide 浙江先锋科技股份有限公司 2024-04-05 — — CN disclosed
US-20140371067-A1 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2014-12-18 — — US disclosed
EP-2793589-A1 HERBICIDAL COMPOUNDS Syngenta Limited (GB) 2014-10-29 — — EP disclosed
US-20140080705-A1 N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-03-20 — — US disclosed
WO-2013144234-A1 1,2,4 -TRIAZOLE DERIVATIVES AS HERBICIDALS SYNGENTA LIMITED (GB) 2013-10-03 — — WO disclosed
EP-2480539-B1 N-(1,2,5-OXADIAZOL-3-YL)BENZAMIDES AND THEIR USE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2013-07-31 — — EP disclosed
WO-2013092834-A1 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2013-06-27 — — WO disclosed
US-8288316-B2 N-(1,2,5-oxadiazol-3-yl)benzamides and their use as herbicides BAYER CROPSCIENCE AG (DE) 2012-10-16 — — US disclosed
US-20110152084-A1 N-(1,2,5-OXADIAZOL-3-YL)BENZAMIDES AND THEIR USE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2011-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140371067-A1 HERBICIDAL COMPOUNDS DDT, GLRX3, AOX1 ALDH1A1 107/4885LMNA 3866/4885PDK1 2823/4885
US-20140080705-A1 N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES PRDX4, CBR3, AOX1 ALDH1A1 370/4885LMNA 3484/4885PDK1 2726/4885
US-20110152084-A1 N-(1,2,5-OXADIAZOL-3-YL)BENZAMIDES AND THEIR USE AS HERBICIDES AOX1, CBR3, ZYX ALDH1A1 109/4885LMNA 3507/4885PDK1 2105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.