SCHEMBL19923449

SCHEMBL19923449

CCC1(CC)C(=O)N([Si](C)(C)C)C(=O)N1c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 10/20 0.44
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 1/20 0.37
CTSG P08311 2/20 0.34
F2 P00734 1/20 0.34
PLG P00747 1/20 0.34
CMA1 P23946 1/20 0.34
CTRC Q99895 1/20 0.34
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
CYP2C19 P33261 3/20 0.33
SHMT2 P34897 1/20 0.33
TSHR P16473 1/20 0.33
PRTN3 P24158 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923650 0.86 ELANE (0.42) ELANENPSR1ALDH1A1CTSGF2
SCHEMBL19923711 0.85 ELANE (0.41) ELANENPSR1ALDH1A1CTSGF2
SCHEMBL19923681 0.85 ELANE (0.41) ELANENPSR1ALDH1A1CTSGF2
SCHEMBL19923633 0.81 ELANE (0.41) ELANENPSR1LMNACYP2C19TSHR
SCHEMBL19923423 0.79 ELANE (0.61) ELANENPSR1
SCHEMBL19923458 0.79 GRM4 (0.44) ELANEALDH1A1LMNACYP2C19
SCHEMBL19923699 0.76 HTR1A (0.35) ELANEALDH1A1PKMTSHR
SCHEMBL19923621 0.76 NPSR1 (0.51) ELANENPSR1ALDH1A1CTSGF2
SCHEMBL19923499 0.75 ALDH1A1 (0.37) ELANEALDH1A1LMNAPKMCYP2C19
SCHEMBL22680911 0.71 LMNA (0.55) ELANENPSR1ALDH1A1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN ELANE 1249/4885NPSR1 1322/4885ALDH1A1 2648/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM ELANE 1276/4885NPSR1 1281/4885ALDH1A1 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.