SCHEMBL19923481

SCHEMBL19923481

C[Si](C)(C)N1C(=O)C(c2ccccc2)N(Cc2ccccc2)C1=O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.49
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44
FPR1 P21462 3/20 0.44
USP2 O75604 1/20 0.44
SMO Q99835 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
F2 P00734 1/20 0.40
PLG P00747 1/20 0.40
ELANE P08246 1/20 0.40
CTSG P08311 1/20 0.40
CMA1 P23946 1/20 0.40
CTRC Q99895 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923492 0.86 EHMT2 (0.46) EHMT2ALDH1A1KDM4EFPR1USP2
SCHEMBL19923669 0.85 LMNA (0.40) ALDH1A1KDM4EFPR1MEN1KMT2A
SCHEMBL19923417 0.85 EHMT2 (0.45) EHMT2ALDH1A1KDM4EFPR1USP2
SCHEMBL19923527 0.84 EHMT2 (0.47) EHMT2ALDH1A1KDM4EFPR1USP2
SCHEMBL19923567 0.82 SMO (0.56) EHMT2SMOMEN1KMT2AF2
SCHEMBL19923642 0.79 EHMT2 (0.49) EHMT2SMOMEN1KMT2AF2
SCHEMBL19923664 0.78 EHMT2 (0.54) EHMT2ALDH1A1MEN1KMT2AF2
SCHEMBL25368139 0.77 EHMT2 (0.49) EHMT2ALDH1A1KDM4ESMOMEN1
SCHEMBL19923468 0.76 LMNA (0.41) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL19923690 0.76 MMP2 (0.36) ALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN EHMT2 54/4885ALDH1A1 2648/4885KDM4E 3471/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM EHMT2 53/4885ALDH1A1 2554/4885KDM4E 3365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.