SCHEMBL19923690

SCHEMBL19923690

C[Si](C)(C)N1C(=O)C(c2ccccc2)N([Si](C)(C)C)C1=O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 8/20 0.36
ALDH1A1 P00352 1/20 0.35
GFER P55789 1/20 0.35
KMT2A Q03164 2/20 0.34
TSHR P16473 1/20 0.34
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 2/20 0.33
BRD4 O60885 2/20 0.33
ADORA3 P0DMS8 1/20 0.33
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923468 0.83 LMNA (0.41) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923553 0.80 MAOA (0.42) ALDH1A1GFERKMT2ATSHRATM
SCHEMBL19923726 0.80 ALDH1A1 (0.43) MMP2ALDH1A1GFERKMT2ASMN1; SMN2
SCHEMBL19923669 0.79 LMNA (0.40) MMP2ALDH1A1KMT2ATSHRATM
SCHEMBL19923698 0.79 MMP2 (0.34) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923724 0.77 MMP2 (0.35) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923481 0.76 EHMT2 (0.49) ALDH1A1KMT2AKDM4E
SCHEMBL19923643 0.76 SMN1; SMN2 (0.37) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923455 0.75 MMP2 (0.33) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923457 0.74 ALDH1A1 (0.49) ALDH1A1KMT2ATSHRNPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20200365943-A1 ADDITIVE FOR BATTERY ELECTROLYTE, LITHIUM ION BATTERY ELECTROLYTE, AND LITHIUM ION BATTERY SHENZHEN BAK POWER BATTERY CO., LTD. (CN) 2020-11-19 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200365943-A1 ADDITIVE FOR BATTERY ELECTROLYTE, LITHIUM ION BATTERY ELECTROLYTE, AND LITHIUM ION BATTERY SOD1, SLC9B2, GRIN2B MMP2 2267/4885ALDH1A1 3144/4885GFER 3952/4885
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN MMP2 1092/4885ALDH1A1 2648/4885GFER 1523/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM MMP2 1416/4885ALDH1A1 2554/4885GFER 1433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.