Sugi Predict

Sugi Predict / Compounds / SCHEMBL19923588

SCHEMBL19923588

SCHEMBL19923588

CCC[Si](CCC)(CCC)N1C(=O)C(c2ccccc2)N(c2ccccc2)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 3/20 0.47
▸ CYP2C9 P11712 3/20 0.47
▸ CYP2C19 P33261 3/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ NPSR1 Q6W5P4 2/20 0.47
▸ MEN1 O00255 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ LMNA P02545 9/20 0.39
▸ ALDH1A1 P00352 5/20 0.39
▸ GFER P55789 1/20 0.39
▸ RECQL P46063 2/20 0.38
▸ KDM4E B2RXH2 3/20 0.38
▸ GAA P10253 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ RXFP1 Q9HBX9 1/20 0.37
▸ CCR1 P32246 1/20 0.36
▸ HPGD P15428 2/20 0.36
▸ CASP3 P42574 1/20 0.36
▸ CYP3A4 P08684 2/20 0.35
▸ MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923545 0.90 CYP1A2 (0.44) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923526 0.82 LMNA (0.44) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923411 0.82 CYP1A2 (0.42) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923726 0.82 ALDH1A1 (0.43) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923598 0.82 SMN1; SMN2 (0.34) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923612 0.81 LMNA (0.38) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923651 0.81 CYP1A2 (0.41) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923417 0.78 EHMT2 (0.45) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL19923540 0.78 GFER (0.39) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923590 0.75 ALDH1A1 (0.48) CYP2C9CYP2C19NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 — — US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 — — US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 — — US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN CYP1A2 1941/4885CYP2C9 1621/4885CYP2C19 1347/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM CYP1A2 1882/4885CYP2C9 1537/4885CYP2C19 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.