SCHEMBL19923540

SCHEMBL19923540

O=C1C(c2ccccc2)N(c2ccccc2)C(=O)N1[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 3/20 0.39
ALDH1A1 P00352 4/20 0.39
LMNA P02545 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
RECQL P46063 1/20 0.38
KDM4E B2RXH2 2/20 0.38
GAA P10253 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
CCR1 P32246 1/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923726 0.83 ALDH1A1 (0.43) GFERALDH1A1LMNASMN1; SMN2CYP1A2
SCHEMBL19923455 0.81 MMP2 (0.33) GFERALDH1A1NPSR1MEN1KMT2A
SCHEMBL19923679 0.81 LOX (0.39) GFERALDH1A1LMNASMN1; SMN2CYP1A2
SCHEMBL19923533 0.80 GRM4 (0.34) GFERALDH1A1LMNAMEN1KMT2A
SCHEMBL19923426 0.79 LMNA (0.40) GFERALDH1A1LMNANPSR1RECQL
SCHEMBL19923545 0.79 CYP1A2 (0.44) GFERALDH1A1LMNASMN1; SMN2CYP1A2
SCHEMBL19923588 0.78 CYP1A2 (0.47) GFERALDH1A1LMNASMN1; SMN2CYP1A2
SCHEMBL19923630 0.76 LMNA (0.38) ALDH1A1LMNASMN1; SMN2CYP1A2CYP2C9
SCHEMBL19923608 0.76 CYP1A2 (0.38) GFERALDH1A1LMNASMN1; SMN2CYP1A2
SCHEMBL2791034 0.75 NPSR1 (0.42) GFERALDH1A1LMNASMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN GFER 1523/4885ALDH1A1 2648/4885LMNA 336/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM GFER 1433/4885ALDH1A1 2554/4885LMNA 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.