SCHEMBL19923622

SCHEMBL19923622

CC[Si](CC)(CC)N1C(=O)C(C)N(Cc2ccccc2)C1=O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMO Q99835 3/20 0.53
EHMT2 Q96KQ7 1/20 0.49
TAS2R8 Q9NYW2 3/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
F2 P00734 1/20 0.40
PLG P00747 1/20 0.40
ELANE P08246 1/20 0.40
CTSG P08311 1/20 0.40
CMA1 P23946 1/20 0.40
CTRC Q99895 1/20 0.40
EP300 Q09472 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923607 0.90 SMO (0.52) SMOEHMT2TAS2R8MEN1KMT2A
SCHEMBL19923567 0.85 SMO (0.56) SMOEHMT2TAS2R8MEN1KMT2A
SCHEMBL19923710 0.84 EHMT2 (0.47) SMOEHMT2MEN1KMT2AMAPT
SCHEMBL19923492 0.83 EHMT2 (0.46) SMOEHMT2MEN1KMT2AMAPT
SCHEMBL19923769 0.82 SMO (0.53) SMOEHMT2TAS2R8MEN1KMT2A
SCHEMBL19923739 0.77 L3MBTL1 (0.34) F2ELANECTSGCTRC
SCHEMBL19923759 0.76 SMO (0.60) SMOEHMT2MEN1KMT2AF2
SCHEMBL19923535 0.76 CYP1A2 (0.40) SMOMEN1KMT2AELANE
SCHEMBL19923475 0.74 EHMT2 (0.46) SMOEHMT2MEN1KMT2AMAPT
SCHEMBL19923417 0.73 EHMT2 (0.45) SMOEHMT2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN SMO 4561/4885EHMT2 54/4885TAS2R8 4102/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM SMO 4608/4885EHMT2 53/4885TAS2R8 4061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.