Sugi Predict

Sugi Predict / Compounds / SCHEMBL19923535

SCHEMBL19923535

SCHEMBL19923535

CC[Si](CC)(CC)N1C(=O)C(C)N(c2ccccc2)C1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.40
▸ CYP2C9 P11712 2/20 0.40
▸ CYP2C19 P33261 2/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ NPSR1 Q6W5P4 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.38
▸ HTT P42858 1/20 0.38
▸ LOX P28300 1/20 0.37
▸ LOXL3 P58215 1/20 0.37
▸ LOXL4 Q96JB6 1/20 0.37
▸ LOXL2 Q9Y4K0 1/20 0.37
▸ CES2 O00748 3/20 0.36
▸ MAOA P21397 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ GFER P55789 1/20 0.35
▸ SMO Q99835 2/20 0.34
▸ ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923411 0.89 CYP1A2 (0.42) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923478 0.83 CYP1A2 (0.39) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923639 0.82 MAOA (0.41) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923545 0.82 CYP1A2 (0.44) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923679 0.81 LOX (0.39) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL5192164 0.76 MAOA (0.41) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923622 0.76 SMO (0.53) MEN1KMT2ASMOELANE
SCHEMBL6713101 0.75 MAOA (0.48) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL9835334 0.73 MAOA (0.47) CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
SCHEMBL19923522 0.73 SMO (0.53) MEN1KMT2AMAOASMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 — — US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 — — US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 — — US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN CYP1A2 1941/4885CYP2C9 1621/4885CYP2C19 1347/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM CYP1A2 1882/4885CYP2C9 1537/4885CYP2C19 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.