SCHEMBL19923658

SCHEMBL19923658

CC1C(=O)N([Si](C)(C)C)C(=O)N1C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.35
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
PABPC1 P11940 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923439 0.77
SCHEMBL19923730 0.77 ADRA2C (0.31) ADRA2C
SCHEMBL19923620 0.75 TP53 (0.33) ADRA2C
SCHEMBL19923670 0.72 L3MBTL1 (0.35)
SCHEMBL19923460 0.72 GRM4 (0.35)
SCHEMBL8597143 0.71 ADRA2C (0.38) ADRA2CKMT2AMEN1PABPC1
SCHEMBL19923424 0.71 TSHR (0.34) KMT2AMEN1
SCHEMBL162704 0.70 ADRA2C (0.41) ADRA2CKMT2AMEN1PABPC1
SCHEMBL11918894 0.70 ADRA2C (0.41) ADRA2CKMT2AMEN1PABPC1
SCHEMBL8826943 0.68 ADRA2C (0.42) ADRA2CKMT2AMEN1PABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN ADRA2C 4563/4885KMT2A 1080/4885MEN1 2213/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM ADRA2C 4579/4885KMT2A 999/4885MEN1 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.