SCHEMBL19923593

SCHEMBL19923593

CN1CC(=O)N([Si](c2ccccc2)(c2ccccc2)c2ccccc2)C1=O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 1/20 0.43
BRD4 O60885 5/20 0.35
ALDH1A1 P00352 3/20 0.34
TSHR P16473 3/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
SRD5A1 P18405 1/20 0.33
CREBBP Q92793 1/20 0.33
USP2 O75604 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923485 0.80 MEN1 (0.32) KMT2AMEN1
SCHEMBL19923512 0.79 NPC1 (0.47) KMT2AMEN1GAAMAPT
SCHEMBL19923473 0.78 GRM4 (0.45) ALDH1A1TSHRKMT2AUSP2MAPT
SCHEMBL19923712 0.78 ACHE (0.35) PLA2G7KMT2AMEN1
SCHEMBL19923482 0.73 ENPP2 (0.48) ALDH1A1TSHRKMT2AMEN1GAA
SCHEMBL19923636 0.71 ALDH1A1 (0.43) ALDH1A1TSHRKMT2AMEN1GAA
SCHEMBL19923660 0.70 PLA2G7 (0.33) PLA2G7BRD4KMT2A
SCHEMBL11276548 0.68 ENPP2 (0.49) PLA2G7ALDH1A1KMT2AMEN1GAA
SCHEMBL19923638 0.67 PLA2G7 (0.45) PLA2G7ALDH1A1GAAHSD17B10L3MBTL1
SCHEMBL19923649 0.66 KMT2A (0.33) PLA2G7ALDH1A1KMT2AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN PLA2G7 2819/4885BRD4 391/4885ALDH1A1 2648/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM PLA2G7 2655/4885BRD4 490/4885ALDH1A1 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.