Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19923432 | 0.86 | ALDH1A1 (0.39) | GRM4ALDH1A1GRM5SMN1; SMN2 | |
| SCHEMBL19923509 | 0.81 | ALDH1A1 (0.36) | GRM4ALDH1A1GRM5SMN1; SMN2USP2 | |
| SCHEMBL19923771 | 0.80 | NPSR1 (0.38) | GRM4ALDH1A1GRM5ELANE | |
| SCHEMBL19923638 | 0.80 | PLA2G7 (0.45) | GRM4ALDH1A1GRM5PLA2G7ELANE | |
| SCHEMBL19923515 | 0.80 | ALDH1A1 (0.37) | GRM4ALDH1A1PLA2G7ELANE | |
| SCHEMBL19923676 | 0.77 | GRM4 (0.45) | GRM4ALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL19923429 | 0.77 | MITF (0.39) | ALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL19923506 | 0.76 | AR (0.39) | ALDH1A1GRM5SMN1; SMN2MARK3PLA2G7 | |
| SCHEMBL19923707 | 0.75 | GRM4 (0.35) | GRM4 | |
| SCHEMBL19923557 | 0.74 | ELANE (0.45) | ALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | BRIDGESTONE CORPORATION (JP) | 2021-01-26 | — | — | US | claimed |
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-03-08 | — | — | US | claimed |
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | BRIDGESTONE CORPORATION (JP) | 2021-01-26 | — | — | US | disclosed |
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | PARG, HNMT, PARN | GRM4 2257/4885ALDH1A1 2648/4885GRM5 2422/4885 |
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | HNMT, PARG, PAM | GRM4 2114/4885ALDH1A1 2554/4885GRM5 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.