Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30235329 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTTHRBNPSR1 | |
| SCHEMBL30235338 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTHRBNPSR1 | |
| SCHEMBL1993111 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTHRBNPSR1 | |
| SCHEMBL1989407 | 0.89 | PANK3 (0.44) | ALDH1A1KDM4EMAPTGAAPANK3 | |
| SCHEMBL30235095 | 0.88 | KCNH2 (0.44) | ALDH1A1KDM4EMAPTNPSR1TSHR | |
| SCHEMBL1991472 | 0.88 | KCNH2 (0.44) | ALDH1A1KDM4EMAPTNPSR1TSHR | |
| SCHEMBL1997118 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTTHRBNPSR1 | |
| SCHEMBL1992803 | 0.88 | REV1 (0.44) | ALDH1A1KDM4EMAPTTHRBNPSR1 | |
| SCHEMBL15161945 | 0.87 | HTR1A (0.44) | ALDH1A1KDM4EMAPTTHRBNPSR1 | |
| SCHEMBL1990361 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTTHRBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9452168-B2 | Pyrrole antifungal agents | F2G LTD (GB) | 2016-09-27 | — | — | US | claimed |
| US-20150238500-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-08-27 | — | — | US | claimed |
| US-8993574-B2 | Pyrrole antifungal agents | F2G LTD (GB) | 2015-03-31 | — | — | US | claimed |
| US-20110152285-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2011-06-23 | — | — | US | claimed |
| US-11065228-B2 | Antifungal agents | F2G LIMITED (GB) | 2021-07-20 | — | — | US | disclosed |
| US-20200179340-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2020-06-11 | — | — | US | disclosed |
| CN-111096967-A | Antifungal agent | F2G有限公司 | 2020-05-05 | — | — | CN | disclosed |
| US-10596150-B2 | Antifungal agents | F2G LIMITED (GB) | 2020-03-24 | — | — | US | disclosed |
| US-20190314333-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2019-10-17 | — | — | US | disclosed |
| US-10201524-B2 | Antifungal agents | F2G LIMITED (GB) | 2019-02-12 | — | — | US | disclosed |
| EP-3415511-A1 | ANTIFUNGAL AGENTS | F2G Limited (GB) | 2018-12-19 | — | — | EP | disclosed |
| EP-3221308-B1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2018-09-19 | — | — | EP | disclosed |
| US-9452168-B2 | Pyrrole antifungal agents | F2G LTD (GB) | 2016-09-27 | — | — | US | disclosed |
| WO-2016079536-A1 | ANTIFUNGAL AGENTS | F2G LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |
| US-20150238500-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-08-27 | — | — | US | disclosed |
| US-8993574-B2 | Pyrrole antifungal agents | F2G LTD (GB) | 2015-03-31 | — | — | US | disclosed |
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| US-20110152285-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200179340-A1 | ANTIFUNGAL AGENTS | DPM1, AADAC, PIK3C3 | ALDH1A1 1484/4885KDM4E 746/4885MAPT 3096/4885 |
| US-20110152285-A1 | PYRROLE ANTIFUNGAL AGENTS | FOXM1, PYCR1, ARG1 | ALDH1A1 219/4885KDM4E 1706/4885MAPT 1696/4885 |
| US-20150238500-A1 | PYRROLE ANTIFUNGAL AGENTS | FOXM1, PYCR1, ARG1 | ALDH1A1 219/4885KDM4E 1706/4885MAPT 1696/4885 |
| US-11065228-B2 | Antifungal agents | DPM1, AADAC, PIK3C3 | ALDH1A1 1484/4885KDM4E 746/4885MAPT 3096/4885 |
| US-20190314333-A1 | ANTIFUNGAL AGENTS | DPM1, AADAC, PIK3C3 | ALDH1A1 1484/4885KDM4E 746/4885MAPT 3096/4885 |
| US-10201524-B2 | Antifungal agents | DPM1, AADAC, PIK3C3 | ALDH1A1 1484/4885KDM4E 746/4885MAPT 3096/4885 |
| US-10596150-B2 | Antifungal agents | DPM1, AADAC, PIK3C3 | ALDH1A1 1484/4885KDM4E 746/4885MAPT 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.