Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | IGFBP5 | P24593 | 2/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925369 | 0.81 | IGFBP5 (0.40) | P4HTMDAOIGFBP5NR3C2IGFBP3 | |
| SCHEMBL19926019 | 0.70 | PRKCI (0.43) | — | |
| SCHEMBL6604473 | 0.67 | ALOX15 (0.54) | IGFBP5CSNK2A2CSNK2BCSNK2A1IGFBP3 | |
| SCHEMBL5516464 | 0.65 | KEAP1 (0.49) | EGFR | |
| SCHEMBL18010609 | 0.65 | THRB (0.50) | P4HTMNR3C2 | |
| SCHEMBL1149419 | 0.64 | DAO (0.71) | DAOPPARG | |
| SCHEMBL29373779 | 0.63 | BCL2L1 (0.65) | — | |
| SCHEMBL12243325 | 0.63 | BCL2L1 (0.65) | — | |
| SCHEMBL12062912 | 0.63 | NR4A2 (0.46) | — | |
| SCHEMBL474878 | 0.63 | AURKA (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-A1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | Suven Life Sciences Limited (IN) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018042362-A1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2018-03-08 | — | — | WO | disclosed |