SCHEMBL19929758

SCHEMBL19929758

CN(C)c1cc(-c2ccccc2)ccc1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.45
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
APAF1 O14727 1/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42
XBP1 P17861 1/20 0.42
PTBP1 P26599 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
GALK1 P51570 1/20 0.42
BLM P54132 1/20 0.42
SMAD3 P84022 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
RXRA P19793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6726810 0.88 MEN1 (0.42) PGRMAPTMEN1APAF1NPC1
SCHEMBL19929759 0.83 PGR (0.45) PGRMAPTMEN1APAF1NPC1
SCHEMBL18594073 0.82 MAPT (0.39) PGRMAPTMEN1APAF1NPC1
SCHEMBL21173403 0.82 PGR (0.44) PGRMAPTMEN1NPC1LMNA
SCHEMBL3786439 0.80 PGR (0.43) PGRMAPTMEN1APAF1NPC1
SCHEMBL30111058 0.80 PGR (0.43) PGRMAPTMEN1LMNAKMT2A
SCHEMBL29926882 0.80 ALOX5 (0.59) PGRKMT2ARXRARXRBALOX5
SCHEMBL16559082 0.79 PGR (0.49) PGRMAPTMEN1APAF1NPC1
SCHEMBL1254512 0.78 ALDH1A1 (0.45) PGRMAPTMEN1LMNAKMT2A
SCHEMBL29433183 0.78 ALDH1A1 (0.45) PGRMAPTMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2024-07-16 US disclosed
US-20180066000-A1 Metal Complexes and Electroluminescent Devices Comprising These Metal Complexes MERCK PATENT GMBH (DE) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, NR2E3 PGR 1452/4885MAPT 746/4885MEN1 798/4885
US-20180066000-A1 Metal Complexes and Electroluminescent Devices Comprising These Metal Complexes OCIAD2, OCIAD1, ICOSLG PGR 3319/4885MAPT 1029/4885MEN1 3880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.