Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 6/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330014 | 0.88 | PPARA (0.43) | MAPTTRPM8RAB9AKDM4ENPC1 | |
| SCHEMBL16398461 | 0.84 | MAPT (0.43) | MAPTTRPM8KCNH2RAB9AKDM4E | |
| SCHEMBL4322468 | 0.80 | PPARA (0.40) | MAPTTRPM8RAB9AKDM4EGAA | |
| SCHEMBL624460 | 0.76 | MAPT (0.44) | MAPTRAB9AKDM4ENPC1POLB | |
| SCHEMBL28292288 | 0.75 | AGER (0.53) | AGERCTRC | |
| SCHEMBL2070188 | 0.73 | SMN1; SMN2 (0.56) | MAPTTRPM8RAB9AKDM4ENPC1 | |
| SCHEMBL16398666 | 0.70 | HTT (0.49) | AGERMAPTTRPM8RAB9AKDM4E | |
| SCHEMBL7186350 | 0.70 | ALDH1A1 (0.41) | RAB9AKDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL21376152 | 0.70 | ALDH1A1 (0.44) | MAPTTRPM8RAB9AKDM4ENPC1 | |
| SCHEMBL18003327 | 0.67 | ALDH1A1 (0.41) | MAPTRAB9AKDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2594555-B1 | HETEROCYCLIC COMPOUND, AND p27 KIP1 DEGRADATION INHIBITOR | ASKA PHARM CO LTD (JP) | 2018-03-07 | — | — | EP | disclosed |