Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4322468 | 0.91 | PPARA (0.40) | PPARARAB9AKDM4EALOX5TRPM8 | |
| SCHEMBL19936638 | 0.88 | AGER (0.43) | RAB9AKDM4ETRPM8GAANPC1 | |
| SCHEMBL12641921 | 0.74 | RAB9A (0.54) | RAB9AKDM4EALOX5TRPM8GAA | |
| SCHEMBL7186350 | 0.71 | ALDH1A1 (0.41) | RAB9AKDM4EALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL16398461 | 0.71 | MAPT (0.43) | RAB9AKDM4EALOX5TRPM8GAA | |
| SCHEMBL13505969 | 0.70 | GCGR (0.44) | RAB9AKDM4EGAAGCGRNPC1 | |
| SCHEMBL13325299 | 0.70 | COMT (0.39) | PPARARAB9AKDM4EALOX5GAA | |
| SCHEMBL12973024 | 0.69 | RAB9A (0.45) | RAB9AKDM4EGAACOMTNPC1 | |
| SCHEMBL15164267 | 0.69 | RAB9A (0.54) | RAB9AKDM4EGCGRNPC1ATM | |
| SCHEMBL27629310 | 0.69 | DHFR (0.47) | PPARAGCGRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014652-B1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-20130217734-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| US-8404726-B2 | Activating agent for peroxisome proliferator activated receptor δ | NIPPON CHEMIPHAR CO. LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20090298896-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO. LTD | 2009-12-03 | — | — | US | disclosed |
| EP-2014652-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298896-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | PPARA, PPARG, PPARD | PPARA 1/4885RAB9A 2594/4885KDM4E 3972/4885 |
| US-20130217734-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | PPARA, PPARG, PPARD | PPARA 1/4885RAB9A 2594/4885KDM4E 3972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.