Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070188 | 0.80 | SMN1; SMN2 (0.56) | ALDH1A1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL16399400 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL18003327 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL16398461 | 0.76 | MAPT (0.43) | ALDH1A1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL18003597 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL18171975 | 0.72 | RAB9A (0.68) | ALDH1A1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL18173829 | 0.72 | SMN1; SMN2 (0.55) | ALDH1A1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL624460 | 0.71 | MAPT (0.44) | ALDH1A1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL19936638 | 0.70 | AGER (0.43) | ALDH1A1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL2557055 | 0.70 | MEN1 (0.42) | ALDH1A1KMT2AKDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656770-A2 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYCLES | Syngenta Participations AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3286187-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |