Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998282 | 0.84 | L3MBTL1 (0.65) | L3MBTL1PTGDR2AKR1C3PKMKMT2A | |
| SCHEMBL28935816 | 0.80 | PTGDR2 (0.40) | PTGDR2AKR1C3AKR1C2KMT2ATSHR | |
| SCHEMBL1994265 | 0.79 | PTGDR2 (0.42) | PTGDR2AKR1C3AKR1C2 | |
| SCHEMBL1993957 | 0.79 | L3MBTL1 (0.44) | L3MBTL1PTGDR2AKR1C3AKR1C2PKM | |
| SCHEMBL1226938 | 0.76 | L3MBTL1 (0.71) | L3MBTL1AKR1C3AKR1C2PKMMAPT | |
| SCHEMBL1995665 | 0.73 | ICMT (0.37) | L3MBTL1PTGDR2TSHRSMN1; SMN2 | |
| SCHEMBL1995369 | 0.71 | L3MBTL1 (0.49) | L3MBTL1PTGDR2AKR1C3AKR1C2KMT2A | |
| SCHEMBL12631148 | 0.70 | PTGDR2 (0.48) | L3MBTL1PTGDR2AKR1C3AKR1C2 | |
| SCHEMBL2779430 | 0.70 | PKM (0.46) | L3MBTL1PKMKMT2ATDP1GAA | |
| SCHEMBL1992109 | 0.69 | PKM (0.58) | PKMKMT2AMAPTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | L3MBTL1 3898/4885PTGDR2 61/4885AKR1C3 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.