Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 13/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990987 | 0.80 | L3MBTL1 (0.45) | PTGDR2FABP4PLA2G2AICMT | |
| SCHEMBL1993789 | 0.79 | L3MBTL1 (0.46) | PTGDR2AKR1C3AKR1C2 | |
| SCHEMBL28935816 | 0.77 | PTGDR2 (0.40) | PTGDR2AKR1C3AKR1C2 | |
| SCHEMBL12631148 | 0.70 | PTGDR2 (0.48) | PTGDR2AKR1C3AKR1C2 | |
| SCHEMBL1993887 | 0.68 | ICMT (0.49) | PTGDR2FABP4ICMT | |
| SCHEMBL28935680 | 0.67 | L3MBTL1 (0.46) | PTGDR2AKR1C3AKR1C2 | |
| SCHEMBL10964741 | 0.65 | FABP4 (0.48) | FABP4 | |
| SCHEMBL1282624 | 0.65 | OPRM1 (0.50) | — | |
| SCHEMBL11086694 | 0.64 | CA2 (0.42) | FABP4 | |
| SCHEMBL11079970 | 0.64 | KMT2A (0.50) | FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | PTGDR2 61/4885FABP4 4529/4885PLA2G2A 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.