SCHEMBL1993791

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127550	0.86	TSHR (0.37)	TRPV1MAPTNPC1RAB9ASMN1; SMN2
	SCHEMBL30234731	0.84	MAPT (0.42)	MAPTNPC1RAB9AALDH1A1USP2
	SCHEMBL1127284	0.84	MAPT (0.42)	MAPTNPC1RAB9AALDH1A1USP2
	SCHEMBL1646393	0.83	MAPT (0.39)	TRPV1MAPTNPC1RAB9ASMN1; SMN2
	SCHEMBL944212	0.83	NPC1 (0.41)	TRPV1MAPTNPC1RAB9ASMN1; SMN2
	SCHEMBL1992685	0.83	MAPT (0.43)	MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
	SCHEMBL1127435	0.82	MAPT (0.40)	TRPV1MAPTNPC1RAB9AALDH1A1
	SCHEMBL1989247	0.82	MAPT (0.40)	MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
	SCHEMBL942618	0.82	NPC1 (0.42)	TRPV1MAPTNPC1RAB9ASMN1; SMN2
	SCHEMBL1991189	0.81	MAPT (0.40)	MAPTNPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.