SCHEMBL1992685

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127284	0.88	MAPT (0.42)	MAPTKMT2AMEN1LMNAALDH1A1
	SCHEMBL30234731	0.88	MAPT (0.42)	MAPTKMT2AMEN1LMNAALDH1A1
	SCHEMBL1989247	0.85	MAPT (0.40)	MAPTKMT2AMEN1LMNAALDH1A1
	SCHEMBL1126869	0.84	NPC1 (0.43)	MAPTKMT2ALMNAALDH1A1POLB
	SCHEMBL1993791	0.83	TRPV1 (0.38)	MAPTLMNAALDH1A1L3MBTL1TSHR
	SCHEMBL1990466	0.82	NPC1 (0.41)	MAPTKMT2AMEN1LMNAALDH1A1
	SCHEMBL1991189	0.80	MAPT (0.40)	MAPTALDH1A1MAPK1HPGDKDM4E
	SCHEMBL1126434	0.79	MAPT (0.39)	MAPTKMT2AMEN1LMNAALDH1A1
	SCHEMBL1127435	0.79	MAPT (0.40)	MAPTKMT2AMEN1LMNAALDH1A1
	SCHEMBL1126732	0.78	MAPT (0.38)	MAPTKMT2AMEN1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.