Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992765 | 0.97 | RECQL (0.56) | RECQLSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL1991988 | 0.84 | TOP2A (0.45) | TOP2APOLBCYP1A2SLC6A4KDM4E | |
| SCHEMBL1995348 | 0.80 | ADRA1A (0.46) | TOP2APOLBCYP1A2SLC6A4KDM4E | |
| SCHEMBL5323230 | 0.78 | SMN1; SMN2 (0.73) | RECQLSMN1; SMN2ALDH1A1L3MBTL1POLB | |
| SCHEMBL1991515 | 0.76 | RECQL (0.55) | RECQLSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL13013370 | 0.75 | ADRA1A (0.43) | TOP2APOLBCYP1A2SLC6A4KDM4E | |
| SCHEMBL1992806 | 0.74 | RECQL (0.51) | RECQLSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL1992805 | 0.74 | RECQL (0.51) | RECQLSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL14979187 | 0.74 | ALDH1A1 (0.64) | RECQLSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL1998303 | 0.74 | RECQL (0.53) | RECQLSMN1; SMN2ALDH1A1SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | RECQL 3604/4885SMN1; SMN2 2548/4885ALDH1A1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.