Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19938508 | 0.90 | OPRK1 (0.33) | OPRK1PDE4DMGLLALDH1A1MEN1 | |
| SCHEMBL19938219 | 0.88 | ALDH1A1 (0.42) | MGLLGAAALDH1A1CES2BCHE | |
| SCHEMBL19938367 | 0.83 | OPRK1 (0.35) | OPRK1PDE4DMGLLGAAALDH1A1 | |
| SCHEMBL19938621 | 0.81 | OPRK1 (0.33) | OPRK1PDE4DMGLLALDH1A1MEN1 | |
| SCHEMBL19939054 | 0.81 | ALDH1A1 (0.42) | MGLLGAAALDH1A1CES2BCHE | |
| SCHEMBL19939092 | 0.81 | GAA (0.37) | MGLLGAAALDH1A1CES2BCHE | |
| SCHEMBL23139912 | 0.79 | ALDH1A1 (0.39) | MGLLGAAALDH1A1CES2BCHE | |
| SCHEMBL19939063 | 0.78 | MGLL (0.37) | MGLLGAAALDH1A1CES2BCHE | |
| SCHEMBL19939124 | 0.78 | CES2 (0.35) | MGLLGAAALDH1A1CES2BCHE | |
| SCHEMBL19938464 | 0.78 | ALDH1A1 (0.33) | MGLLGAAALDH1A1CES2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11653565-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-05-16 | — | — | US | disclosed |
| US-11653565-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-05-16 | — | — | US | disclosed |
| US-20200220083-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2020-07-09 | — | — | US | disclosed |
| US-10686141-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2020-06-16 | — | — | US | disclosed |
| US-20180069182-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2018-03-08 | — | — | US | disclosed |
| US-20180069182-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11653565-B2 | Polycyclic aromatic compound | ETV6, EBPL, EML4 | OPRK1 1573/4885PDE4D 4783/4885MGLL 3731/4885 |
| US-10686141-B2 | Polycyclic aromatic compound | ETV6, EBPL, EML4 | OPRK1 1573/4885PDE4D 4783/4885MGLL 3731/4885 |
| US-20180069182-A1 | POLYCYCLIC AROMATIC COMPOUND | ETV6, EBPL, EML4 | OPRK1 1573/4885PDE4D 4783/4885MGLL 3731/4885 |
| US-20200220083-A1 | POLYCYCLIC AROMATIC COMPOUND | ETV6, EBPL, EML4 | OPRK1 1573/4885PDE4D 4783/4885MGLL 3731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.