Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127104 | 0.86 | BRD4 (0.47) | BRD4CREBBPHSD11B1 | |
| Biphenyl SCHEMBL27321119 | 0.66 | DNM1 (0.46) | TSHRHSD11B1MEN1KMT2A | |
| SCHEMBL1992653 | 0.66 | CNR1 (0.44) | TSHRBRD4CNR1CNR2MEN1 | |
| Toluene SCHEMBL1752732 | 0.65 | TSHR (0.55) | TSHRCNR2 | |
| SCHEMBL1126708 | 0.65 | BRD4 (0.47) | BRD4CREBBP | |
| SCHEMBL14288455 | 0.65 | TSHR (0.50) | TSHRBRD4HSD11B1NR1H3TLR8 | |
| Benzene SCHEMBL11774008 | 0.64 | TSHR (0.40) | TSHRMEN1KMT2A | |
| SCHEMBL9438110 | 0.64 | LTA4H (0.42) | TSHRHSD11B1MEN1KMT2A | |
| SCHEMBL14288449 | 0.63 | TLR8 (0.47) | TSHRTLR8CNR1CNR2 | |
| Bromobenzene SCHEMBL30480746 | 0.62 | ALDH1A1 (0.50) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152285-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152285-A1 | PYRROLE ANTIFUNGAL AGENTS | FOXM1, PYCR1, ARG1 | TSHR 1769/4885BRD4 3630/4885CREBBP 4702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.