Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP9 | P55211 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 5/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 8/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.42 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944859 | 0.87 | ITGB3 (0.49) | PSMB8PSMB5 | |
| SCHEMBL20052422 | 0.83 | CASP3 (0.56) | CASP3CASP1CASP9CASP7MMP9 | |
| SCHEMBL20356100 | 0.83 | CASP3 (0.56) | CASP3CASP1CASP9CASP7MMP9 | |
| SCHEMBL15462721 | 0.83 | CASP3 (0.56) | CASP3CASP1CASP9CASP7MMP9 | |
| SCHEMBL20356098 | 0.78 | CASP3 (0.49) | CASP3CASP1CASP9CASP7MMP9 | |
| SCHEMBL19015945 | 0.77 | CASP3 (0.49) | CASP3CASP1CASP9CASP7PSMB8 | |
| SCHEMBL18471954 | 0.76 | CASP3 (0.69) | CASP3CASP1CASP9CASP7PSMB5 | |
| SCHEMBL19015827 | 0.76 | CASP3 (0.46) | CASP3CASP1CASP9CASP7PSMB8 | |
| SCHEMBL19944565 | 0.74 | ITGB3 (0.47) | MMP9MMP8PSMB8PSMB5MMP2 | |
| SCHEMBL697840 | 0.74 | MMP9 (0.74) | MMP9MMP8MMP13ADAMTS4MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697246-B1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-03-07 | — | — | EP | disclosed |