Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 8/20 | 0.61 |
| ▸ | CASP7 | P55210 | 5/20 | 0.61 |
| ▸ | CASP1 | P29466 | 4/20 | 0.61 |
| ▸ | CASP9 | P55211 | 2/20 | 0.61 |
| ▸ | CASP4 | P49662 | 2/20 | 0.61 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.61 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 6/20 | 0.51 |
| ▸ | LGMN | Q99538 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052410 | 0.91 | CASP3 (0.58) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19944785 | 0.91 | CASP3 (0.58) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL15462666 | 0.85 | CASP3 (0.73) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19944654 | 0.84 | CASP1 (0.66) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18782028 | 0.80 | CASP3 (0.77) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL11112981 | 0.80 | CYP3A4 (0.53) | CTSLCTSBMAPK1 | |
| SCHEMBL29434574 | 0.78 | CTSB (0.62) | CTSLCTSBMAPK1 | |
| SCHEMBL29434511 | 0.77 | CTSB (0.56) | CTSLCTSB | |
| SCHEMBL15462686 | 0.76 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL29544585 | 0.76 | REN (0.54) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697246-B1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-03-07 | — | — | EP | disclosed |