Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | CASP4 | P49662 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | CASP9 | P55211 | 1/20 | 0.66 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.66 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.66 |
| ▸ | CTSL | P07711 | 13/20 | 0.65 |
| ▸ | CTSB | P07858 | 7/20 | 0.58 |
| ▸ | CTSK | P43235 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15462666 | 0.87 | CASP3 (0.73) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL19944919 | 0.85 | CASP3 (0.70) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL19944665 | 0.84 | CASP3 (0.61) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL27543993 | 0.82 | PSMB1 (0.71) | CTSLCTSBCTSK | |
| SCHEMBL4427171 | 0.82 | PSMB1 (0.71) | CTSLCTSBCTSK | |
| SCHEMBL19944562 | 0.81 | CTSL (0.54) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL7612532 | 0.80 | CTSK (0.71) | CTSLCTSBCTSK | |
| SCHEMBL7612544 | 0.80 | CTSK (0.71) | CTSLCTSBCTSK | |
| SCHEMBL19944650 | 0.80 | CASP3 (0.66) | CASP1CASP3CASP7CASP9CASP10 | |
| SCHEMBL30070594 | 0.80 | CTSL (0.76) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697246-B1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-03-07 | — | — | EP | disclosed |