Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901721 | 0.87 | TYMP (0.38) | MEN1KMT2ACCR2KCNH2ALDH1A1 | |
| SCHEMBL19947248 | 0.80 | BCHE (0.40) | MEN1KMT2ACCR2KCNH2ITGB3 | |
| Trifluoroacetic Acid SCHEMBL3335491 | 0.78 | DPP4 (0.35) | KCNH2ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL3335481 | 0.78 | DPP4 (0.35) | KCNH2ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL3338294 | 0.78 | DPP4 (0.35) | KCNH2ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL29823097 | 0.77 | HPGD (0.40) | KMT2AITGB3ITGA2BSMN1; SMN2L3MBTL3 | |
| Trifluoroacetic Acid SCHEMBL30528682 | 0.76 | CCR2 (0.40) | MEN1KMT2ACCR2KCNH2ALDH1A1 | |
| SCHEMBL24183650 | 0.76 | HTR6 (0.32) | CCR2KCNH2L3MBTL3L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL30528663 | 0.75 | MEN1 (0.37) | MEN1KMT2ACCR2KCNH2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL994467 | 0.74 | GABRP (0.35) | L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246462-B2 | Chemokine receptor modulators and uses thereof | FLX BIO, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-20180072743-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | RAPT THERAPEUTICS, INC. | 2018-03-15 | — | — | US | disclosed |
| WO-2018049271-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | FLX BIO, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246462-B2 | Chemokine receptor modulators and uses thereof | ACKR3, CCR5, CXCR3 | MEN1 4834/4885KMT2A 4753/4885CCR2 5/4885 |
| US-20180072743-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | ACKR3, CCR5, CXCR3 | MEN1 4834/4885KMT2A 4753/4885CCR2 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.