Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.44 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | DTYMK | P23919 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995835 | 0.88 | KDM4E (0.46) | KDM4EPKMPIK3CDPIK3R2PIK3CA | |
| SCHEMBL1993899 | 0.83 | L3MBTL1 (0.48) | KDM4EPKML3MBTL1PIK3CDPIK3R2 | |
| SCHEMBL1991648 | 0.77 | L3MBTL1 (0.62) | KDM4EPKML3MBTL1GPR119CHRM2 | |
| SCHEMBL14995622 | 0.75 | KDM4E (0.44) | KDM4EPKMPIK3CDPIK3R2PIK3CA | |
| SCHEMBL18605495 | 0.75 | MEN1 (0.40) | KDM4EPKMGPR119LMNA | |
| SCHEMBL5763294 | 0.74 | LMNA (0.49) | KDM4EPKMGPR119LMNATHRB | |
| SCHEMBL23022536 | 0.74 | BRD4 (0.47) | KDM4EPKMLMNATHRBTP53 | |
| SCHEMBL1994908 | 0.74 | L3MBTL1 (0.50) | L3MBTL1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL2002226 | 0.74 | L3MBTL1 (0.50) | KDM4EPKML3MBTL1GPR119LMNA | |
| SCHEMBL23915515 | 0.73 | NPC1 (0.49) | KDM4EPKMPIK3CDPIK3R2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | KDM4E 3351/4885PKM 833/4885L3MBTL1 3898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.