SCHEMBL19952989

SCHEMBL19952989

C=C[Si](Oc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
LTA4H P09960 1/20 0.35
ALDH1A1 P00352 1/20 0.32
CA4 P22748 1/20 0.32
THRB P10828 1/20 0.31
TGM2 P21980 1/20 0.30
KCNA3 P22001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL569492 0.79 ALDH1A1 (0.36) TSHRALDH1A1
SCHEMBL22654178 0.78 TSHR (0.35) TSHRLTA4HALDH1A1CA4THRB
SCHEMBL6890056 0.77 ALDH1A1 (0.35) TSHRALDH1A1
SCHEMBL2231435 0.76 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL294669 0.76 ALDH1A1 (0.33) TSHRALDH1A1CA4
SCHEMBL9901171 0.76 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL22563739 0.75 LTA4H (0.39) TSHRLTA4HALDH1A1CA4THRB
SCHEMBL80762 0.75 LTA4H (0.39) TSHRLTA4HALDH1A1CA4THRB
SCHEMBL3336289 0.75 LTA4H (0.39) TSHRLTA4HALDH1A1CA4THRB
SCHEMBL841999 0.74 ALDH1A1 (0.32) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018048297-A1 ORGANOSILOXANE HYBRID COMPOSITION FOR ENCAPSULATION OF LIGHT-EMITTING ELEMENTS PENCHEM TECHNOLOGIES SDN. BHD. (MY) 2018-03-15 WO claimed
WO-2018048297-A1 ORGANOSILOXANE HYBRID COMPOSITION FOR ENCAPSULATION OF LIGHT-EMITTING ELEMENTS PENCHEM TECHNOLOGIES SDN. BHD. (MY) 2018-03-15 WO disclosed