Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | EPM2A | O95278 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 5/20 | 0.36 |
| ▸ | GABRD | O14764 | 5/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964535 | 0.83 | CYP2A6 (0.40) | MIFEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL19953210 | 0.83 | CYP2A6 (0.46) | MIFEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL19953212 | 0.76 | KAT2B (0.37) | MIFEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL13907589 | 0.75 | HSP90AA1 (0.47) | CYP2A6LMNA | |
| SCHEMBL13907574 | 0.72 | CYP2A6 (0.36) | CYP2A6LMNADYRK1A | |
| SCHEMBL5019781 | 0.70 | KDM4E (0.48) | MIFEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL29466898 | 0.70 | KDM4E (0.48) | MIFEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL19953250 | 0.70 | GPR35 (0.42) | EPM2APTPN2PTPN1PTPN22PIM1 | |
| SCHEMBL216673 | 0.69 | EPM2A (0.53) | MIFEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL29432245 | 0.69 | EPM2A (0.53) | MIFEPM2APTPN2PTPN1PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |