Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953582 | 0.92 | GRM7 (0.41) | GRM7PYGLPYGMTHRBTRPV1 | |
| SCHEMBL19953484 | 0.73 | GRM7 (0.43) | GRM7PYGLPYGMTRPV1MEN1 | |
| SCHEMBL19960700 | 0.71 | GRM7 (0.43) | GRM7PYGLPYGMTRPV1MEN1 | |
| SCHEMBL19953508 | 0.66 | HRH3 (0.46) | GRM7NPC1LMNARAB9A | |
| SCHEMBL19960710 | 0.65 | GRM7 (0.41) | GRM7PYGLPYGMMEN1KMT2A | |
| SCHEMBL19960571 | 0.64 | GRM7 (0.39) | GRM7MEN1KMT2ANPC1LMNA | |
| SCHEMBL31637765 | 0.63 | CA1 (0.61) | GRM7 | |
| SCHEMBL19953537 | 0.63 | GRM7 (0.39) | GRM7PYGLPYGMTRPV1MEN1 | |
| SCHEMBL19960705 | 0.62 | PRMT5 (0.34) | GRM7TRPV1 | |
| SCHEMBL19953584 | 0.62 | FABP5 (0.43) | GRM7MEN1KMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | claimed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |