Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953561 | 0.79 | OPRM1 (0.39) | OPRM1OPRK1OPRL1MEN1KMT2A | |
| SCHEMBL19953500 | 0.67 | FABP5 (0.44) | GRM7HRH3MTNR1AMTNR1BMAPT | |
| SCHEMBL1029693 | 0.65 | MTNR1A (0.77) | GRM7HRH3MTNR1AMTNR1BMAPT | |
| SCHEMBL30595323 | 0.65 | MTNR1A (0.77) | GRM7HRH3MTNR1AMTNR1BMAPT | |
| SCHEMBL19953508 | 0.64 | HRH3 (0.46) | GRM7HRH3MTNR1AMTNR1BMAPT | |
| SCHEMBL19953582 | 0.64 | GRM7 (0.41) | GRM7NPC1LMNARAB9AMEN1 | |
| SCHEMBL9851524 | 0.63 | GRM7 (0.59) | GRM7HRH3MTNR1AMTNR1BMAPT | |
| SCHEMBL8705275 | 0.62 | KMT2A (0.47) | OPRM1OPRK1OPRL1NPC1LMNA | |
| SCHEMBL4486212 | 0.62 | ACE (0.45) | OPRM1MME | |
| SCHEMBL6502466 | 0.62 | MEN1 (0.55) | GRM7HRH3MTNR1AMTNR1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |