Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 7/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954641 | 0.82 | NR3C1 (0.35) | HRH3NR3C1 | |
| SCHEMBL19953968 | 0.81 | KDM4E (0.39) | DRD2DRD4DRD3 | |
| SCHEMBL25745817 | 0.81 | KDM4E (0.42) | DRD2DRD4DRD3 | |
| SCHEMBL25745825 | 0.80 | DRD2 (0.39) | DRD2DRD4DRD3TLR9TLR8 | |
| SCHEMBL25745828 | 0.80 | KDM4E (0.44) | — | |
| SCHEMBL18161167 | 0.79 | DRD2 (0.42) | DRD2DRD4DRD3HRH3NR3C1 | |
| SCHEMBL24815012 | 0.78 | DRD2 (0.40) | DRD2DRD4DRD3TLR9TLR8 | |
| SCHEMBL24006953 | 0.78 | ALOX15 (0.35) | DRD2DRD4DRD3HRH3KDM5A | |
| SCHEMBL25745827 | 0.77 | DRD2 (0.41) | DRD2DRD4DRD3 | |
| SCHEMBL19953969 | 0.77 | TGFBR1 (0.40) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914706-B2 | N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-13 | — | — | US | disclosed |